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CRMP-2(Phospho Thr514) Polyclonal Antibody, 20ul Cell Transfection Interacts with CRSP2 and CRSP6

SKU: 12486615031

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CRMP-2(Phospho Thr514) Polyclonal Antibody, 20ul Cell Transfection Interacts with CRSP2 and CRSP6This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo and hetero tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological

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Description

Interacts with CRSP2 and CRSP6

as it contains characteristic adjacent cysteine residues

Demethylates both di- and trimethylated H3 'Lys-9' residue

Mutations in this gene cause Gitelman syndrome| a disease similar to Bartter's syndrome| that is characterized by hypokalemic alkalosis combined with hypomagnesemia| low urinary calcium| and increased renin activity associated with normal blood pressure

belongs to the plexin family

CRMP-2(Phospho Thr514) Polyclonal Antibody, 20ul Cell Transfection Interacts with CRSP2 and CRSP6This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo and hetero tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological

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